Our focus is ensuring your ingredients and finished products are meeting specification. Alkemist Labs offers high throughput HPTLC and Microscopic analysis for Botanical Ingredient Identity Testing of whole herbs and plant extracts with a standard 5-business day turn-around time.
We are pioneers in the natural products testing industry and have assisted thousands of natural product companies approach, achieve and maintain cGMP compliance in this newly regulated industry.
We work with our clients to ensure test methods are appropriate for their intended use by identifying and using an appropriate scientifically valid method for each established specification.
HPLC/UPLC High Performance Liquid Chromatography (HPLC) and Ultra Performance Liquid Chromatography (UPLC) are considered the most powerful tools in analytical chemistry used to separate, identify, and quantitate compounds in a variety of sample matrices. HPLC/UPLC can be used to assess the purity of samples from a variety of matrices that are able to be dissolved in a liquid/solvent. It oftentimes is able to quantify compounds and adulterants at very low concentrations. This technique is applicable to the accurate quantitation of many different types of chemical constituents of crude raw botanicals from powdered to whole form, extract (powdered or liquid) and finished products/blends as well as all vitamins and amino acids and is a preferred technique worldwide.
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GC Gas chromatography is a term used to describe the group of analytical separation techniques used to analyze volatile substances in the gas phase. In gas chromatography, the components of a sample are dissolved in a solvent and vaporized in order to separate the analytes by distributing the sample between two phases: a stationary phase and a mobile phase. The mobile phase is a chemically inert gas that serves to carry the molecules of the analyte through the heated column and then through the one of the various detectors used, where the separated compounds are identified by comparing with known compounds. This technique is the preferred method for the quantitation of the various components of Fish Oils, oils in general or many of the essential/volatile oils of botanicals as well as a wide variety of combustible compounds found in many different matrices.
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UV VIS Ultraviolet-visible spectroscopy or ultraviolet-visible spectrophotometry (UV-Vis or UV/Vis) refers to absorption spectroscopy in the ultraviolet–visible spectral region. This means it uses light in the visible and adjacent (near-UV and near-infrared (NIR)) ranges. UV/Vis spectroscopy is routinely used in the quantitative determination of solutions of highly conjugated organic compounds, and biological macromolecules. UV/Vis spectroscopy is frequently used to quantitate organic compounds found in many natural products and Dietary Supplements but has the limitation of not being as specific or accurate as HPLC or GC but could be a quick and easy way of quantitating compounds or groups of compounds for ‘process control’ or when one needs a reproducible way of measuring the quality of any material such as an extract or botanical without the need for the specificity of more accurate techniques.
WET CHEMISTRY Wet Chemistry is analysis performed in the liquid phase, generally. Wet chemistry contains many different types of methods such as Titration, Gravimetric analysis, Moisture, pH, Specific Gravity, Loss on Drying, Ash, Environmental and some Elemental analyses of samples. Generally, Wet Chemistry is sometimes used to analyze single components in samples to which the method is targeted but due to the non-specific nature of the wet chemistry methods it is frequently only able to measure larger groups/classes of compounds versus single markers, hence is not as accurate as HPLC or GC.
